Randy is the principal investigator of the lab and a Professor in the section of Cell and Developmental Biology within the Division of Biological Sciences at UCSD. Randy received his Ph.D. from the University of Wisconsin-Madison, and did his postdoctoral work at UC Berkeley. In his free time, Randy enjoys playing the banjo.
Omar is a graduate student who received his B.S. in Biochemistry from the University of California, Davis. He is examining the mechanisms by which Hrd1p and Hrd3p function in ER-Associated Degradation.
Sergey is a staff research associate who received his Masters degree from the University of Southern California. While keeping busy maintaining the administrative operations of the lab, he is also hard at work at the bench, exploring the degradation of HMG-R.
Sarah is a graduate student who recieved her B.S. in Molecular Biology and Biochemistry from the University of Idaho. She is studying the role of Hrd3p in the degradation of ER quality control substrates. In her spare time, Sarah enjoys skiing, traveling, and laughing at Jarrod's robot jokes.
Tai is a graduate student in the lab studying in detail the structural transition of Hmg2p.
Christine is a graduate student who received her B.S. in Biochemistry from the University of Nevada, Reno. She is interested in how Hmg2p acts as a proliferant of the ER. When Christine is not in the lab, she enjoys vegging on the beach, reading, and swimming.
Renee is a graduate student studying ER degradation and the HRD proteins.
Jarrod is a graduate student who received a B.A. in Biology and a B.A. in Chemistry from Minnesota State University Moorhead. He is examining the cytosolic quality control pathway. He has an affinity for robot jokes, Kung Fu and Surfing.
Brian is a graduate student who received his B.A. in Molecular and Cell Biology from the University of California, Berkeley. He is examining the mechanism of retrotranslocation of misfolded proteins in ER associated degradation.
Although he does not have an official title, Buddy is a vital member of the lab. His research interests include anything that anyone else is interested in. In his spare time, Buddy enjoys growing slowly in order to frustrate the other lab members.
Alex was a graduate student in the lab and received his Ph.D. in 2004. His work elucidated the structural transition in Hmg2p that underpins its regulated degradation by the ER quality control apparatus.
Alex's Dissertation: PDF (15.9MB)
Alex is currently a Scientific Database Currator at the Artificial Intelligence Center of SRI International.
He can be reached at: email@example.com
Thomas was an undergraduate and a masters student in the lab who left us upon earning his B.S./M.S. in 2004. He is currenly a graduate student in the History and Philosophy of Science at the University of Pittsburgh
Matt was an undergraduate in the lab who left us to start Graduate School at U.C. Davis.
After working as a lab assistant for two and a half years and studying aspects of Hrd1p physiology, Tuyet plans to teach Biology or Chemistry, and is pursuing her teaching credential at Cal State San Marcos.
She can be reached at: firstname.lastname@example.org
Isabelle Flury came to us from the University of Fribourg in Switzerland, where she earned her Ph.D. in the lab of Andreas Conzelmann. As a Post-Doctoral Fellow from 2001 to 2003, her work revealed the role of the yeast INSIG homologs in the regulation of Hmg2p degradation.
Nathan was a graduate student in the lab and received his Ph.D. in 2002. Nathan's work centered on the discovery and characterization of genes required for Hmg2p degradation, most notably the key ubiquitin ligase Hrd1p.
NB's Doctoral Dissertation: PDF (27.1MB)
Nathan is currently a Senior Research Biochemist with Merck in Boston.
He can be reached at: email@example.com
Stephen was a graduate student in the lab and received his Ph.D. in 2002. His thesis work on the mechanism of the control of Hmg2p degradation led to his discovery and characterization of COD1, a gene with a panoply of ER-related phenotypes.
Stephen is an Assistant Professor of Biology at Ave Maria University in Florida.
He can be reached at:firstname.lastname@example.org
Richard was a graduate student in the lab and received his Ph.D. in June 2000. His graduate project entailed studying the in cis determinants for Hmg2p degradation.
RG's Doctoral Dissertation: PDF (12.3MB)
He has relocated to the Fred Hutchinson Cancer Research Center in Seattle, where he will be studying ubiquitin-mediated processes in silencing for his post-doctoral studies. His new lab address is:
Fred Hutchinson Cancer Research Center
1100 Fairview Avenue North, Mailstop A3-025
Seattle, Washington 98109
Lab Phone: (206) 667-6660
Lynne was an undergraduate in the lab and became a lab assistant after receiving her B.S. from UCSD. She married a Brit and is currently living in England.
Sharon Kim Wilhovsky
Sharon was a graduate student in the lab. She left the program with a Masters and is now a technical writer at Invitrogen.
Linda Phillips Seelig
Linda was a staff research assistant. She and her husband have just returned to the U.S. after living in Argentina for a year.
Johanna was an undergraduate in the lab and became a lab assistant after receiving her B.S. from UCSD. Johanna is currently pursuing a nursing career.
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